Pitcher Paul Maholm will be played by Nick Swardson, better known as Terry the gay prostitute from Reno 911!
More-motivated 2B Jose Castillo will still played by Looney Tunes' Slowpoke Rodriguez, just because I love the picture of Slowpoke so much.
Perennial Prospective Owner Mark Cuban will be played by American Idol's Taylor Hicks
Owner Bob Nutting will be portrayed by Redskins owner Daniel Snyder
Owner G. Ogden Nutting will be played by The Simpsons' miserly millionaire C. Montgomery Burns. Note the extra similarity that they both go by their first initial.
Kevin McClatchy, whipping boy of the Nuttings, will naturally be played by Waylon Smithers